We ran into a mouse cursor issue the other day where it just dissapears after moving your mouse over text inside of a program like Word for example.
Turns out the user had set the DPI to the "Larger - 150%" setting, once this is turned back down to "Smaller - 100% (default)" the mouse cursor works fine.
Found another workaround where you set the mouse to a different icon set in mouse properties and the cursors work again. Seems the "Aero" icon set (default mouse icons) is the one with the problem at the 150% display size.